Decoglurant

Modify Date: 2024-01-02 17:32:31

Decoglurant Structure
Decoglurant structure
Common Name Decoglurant
CAS Number 911115-16-7 Molecular Weight 447.33600
Density N/A Boiling Point N/A
Molecular Formula C21H11F6N5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Decoglurant


Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3. Decoglurant is developed as an antidepressant[1].

 Names

Name 5-[2-[7-(trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]ethynyl]pyridin-2-amine
Synonym More Synonyms

 Decoglurant Biological Activity

Description Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3. Decoglurant is developed as an antidepressant[1].
Related Catalog
Target

mGluR2

mGluR3

References

[1]. Wilkinson ST, et al. A new generation of antidepressants: an update on the pharmaceutical pipeline for novel and rapid-acting therapeutics in mood disorders based on glutamate/GABA neurotransmitter systems. Drug Discov Today. 2019 Feb;24(2):606-615.

 Chemical & Physical Properties

Molecular Formula C21H11F6N5
Molecular Weight 447.33600
Exact Mass 447.09200
PSA 69.83000
LogP 4.74100

 Synonyms

Decoglurant
UNII-5VX4P0JKC5