benzyl 1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenylpyrazole-4-carboxylate

Modify Date: 2024-01-11 20:13:24

benzyl 1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenylpyrazole-4-carboxylate Structure
benzyl 1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenylpyrazole-4-carboxylate structure
Common Name benzyl 1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenylpyrazole-4-carboxylate
CAS Number 913376-52-0 Molecular Weight 380.43700
Density N/A Boiling Point N/A
Molecular Formula C22H24N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name benzyl 1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenylpyrazole-4-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C22H24N2O4
Molecular Weight 380.43700
Exact Mass 380.17400
PSA 73.46000
LogP 3.07530

 Safety Information

HS Code 2933199090

 Synthetic Route

~26%

benzyl 1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenylpyrazole-4-carboxylate Structure

benzyl 1-(2-hyd...

CAS#:913376-52-0

Literature: Amgen Inc. Patent: WO2006/116713 A1, 2006 ; Location in patent: Page/Page column 116-117 ; WO 2006/116713 A1

~40%

benzyl 1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenylpyrazole-4-carboxylate Structure

benzyl 1-(2-hyd...

CAS#:913376-52-0

Literature: Siegmund, Aaron; Retz, Daniel; Xi, Ning; Dominguez, Celia; Buerli, Roland; Liu, Longbin Synlett, 2008 , # 7 p. 1005 - 1008

~41%

benzyl 1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenylpyrazole-4-carboxylate Structure

benzyl 1-(2-hyd...

CAS#:913376-52-0

Literature: Liu, Longbin; Siegmund, Aaron; Xi, Ning; Kaplan-Lefko, Paula; Rex, Karen; Chen, April; Lin, Jasmine; Moriguchi, Jodi; Berry, Loren; Huang, Liyue; Teffera, Yohannes; Yang, Yajing; Zhang, Yihong; Bellon, Steven F.; Lee, Matthew; Shimanovich, Roman; Bak, Annette; Dominguez, Celia; Norman, Mark H.; Harmange, Jean-Christophe; Dussault, Isabelle; Kim, Tae-Seong Journal of Medicinal Chemistry, 2008 , vol. 51, # 13 p. 3688 - 3691

~%

benzyl 1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenylpyrazole-4-carboxylate Structure

benzyl 1-(2-hyd...

CAS#:913376-52-0

Literature: Liu, Longbin; Norman, Mark H.; Lee, Matthew; Xi, Ning; Siegmund, Aaron; Boezio, Alessandro A.; Booker, Shon; Choquette, Debbie; D'Angelo, Noel D.; Germain, Julie; Yang, Kevin; Yang, Yajing; Zhang, Yihong; Bellon, Steven F.; Whittington, Douglas A.; Harmange, Jean-Christophe; Dominguez, Celia; Kim, Tae-Seong; Dussault, Isabelle Journal of Medicinal Chemistry, 2012 , vol. 55, # 5 p. 1868 - 1897

 Customs

HS Code 2933199090
Summary 2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

benzyl 1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylate