7’-OH-N-trityl morpholinothymine

Modify Date: 2024-01-03 00:13:26

7’-OH-N-trityl morpholinothymine Structure
7’-OH-N-trityl morpholinothymine structure
Common Name 7’-OH-N-trityl morpholinothymine
CAS Number 914361-76-5 Molecular Weight 483.56
Density N/A Boiling Point N/A
Molecular Formula C29H29N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 7’-OH-N-trityl morpholinothymine


7’-OH-N-trityl morpholinothymine (PMO Thymidine Precusor) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-((2R,6S)-6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
Synonym More Synonyms

 7’-OH-N-trityl morpholinothymine Biological Activity

Description 7’-OH-N-trityl morpholinothymine (PMO Thymidine Precusor) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C29H29N3O4
Molecular Weight 483.56
Exact Mass 483.21600
PSA 87.56000
LogP 2.96670

 Synonyms

7-hydroxy-N-trityl morpholinothymidine
2-hydroxymethyl-4-trityl-6-(thymin-1-yl)morpholine
1-((2R,6S)-6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-5-methylpyrimidine-2,4-(1H,3H)-dione
7'-OH-N-trityl morpholino thymine
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