PB2
Modify Date: 2025-08-20 22:23:20
PB2 structure
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Common Name | PB2 | ||
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| CAS Number | 914940-24-2 | Molecular Weight | 286.11 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H20BO2P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PB2PB2 is a tris(2-carboxyethyl)phosphine (TCEP) analogue increasing retinal ganglion (RGCs) cells survival after axotomy in vitro at nanomolar and picomolar concentrations. PB2 is substantially more permeable than TCEP. PB2, as a reducing agent, is highly neuroprotective for RGCs[1]. |
| Name | PB2 |
|---|
| Description | PB2 is a tris(2-carboxyethyl)phosphine (TCEP) analogue increasing retinal ganglion (RGCs) cells survival after axotomy in vitro at nanomolar and picomolar concentrations. PB2 is substantially more permeable than TCEP. PB2, as a reducing agent, is highly neuroprotective for RGCs[1]. |
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| Related Catalog | |
| In Vitro | PB2 (0.001~100000 nM; 72 hours; RGCs) increases RGC viability[1]. PB2 has modifications that neutralize the polarity of the compounds. The methylesters of PB2 is likely to be cleaved by cytosolic esterases, yielding a polar intracellular intermediate that would be unlikely to cross cell membranes[1]. Cell Viability Assay[1] Cell Line: RGCs Concentration: 0.001~100000 nM Incubation Time: 72 hours Result: Increased RGC viability. |
| References |
| Molecular Formula | C16H20BO2P |
|---|---|
| Molecular Weight | 286.11 |