SCH-900271

Modify Date: 2024-09-19 06:46:13

SCH-900271 structure	Common Name	SCH-900271
	CAS Number	915210-50-3	Molecular Weight	276.28800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₆N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SCH-900271

SCH-900271 is an orally active, potent nicotinic acid receptor (NAR) agonist with an EC50 of 2 nM in the hu-GPR109a assay. SCH-900271 exhibits dose-dependent inhibition of plasma free fatty acid (FFA). SCH-900271 has an improved therapeutic window to flushing[1].

Name	5-[3-(1-methylcyclopropyl)propyl]-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione
Synonym	More Synonyms

Description	SCH-900271 is an orally active, potent nicotinic acid receptor (NAR) agonist with an EC50 of 2 nM in the hu-GPR109a assay. SCH-900271 exhibits dose-dependent inhibition of plasma free fatty acid (FFA). SCH-900271 has an improved therapeutic window to flushing[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Metabolic Disease
Target	EC50: 2.0 nM (hu-GPR109a), 96 nM (hu-GPR109b), 8.0 nM (rat-GPR109a), 6.0 nM (m-GPR109a) and 5.0 nM (dog-GPR109a)[1]
References	[1]. Anandan Palani, et al. Discovery of SCH 900271, a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia. ACS Med Chem Lett. 2011 Nov 24;3(1):63-8.

Molecular Formula	C₁₄H₁₆N₂O₄
Molecular Weight	276.28800
Exact Mass	276.11100
PSA	96.45000
LogP	2.11700

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SCH-900271
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: SCH900271
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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