Irloxacin

Modify Date: 2024-01-09 14:49:55

Irloxacin Structure
Irloxacin structure
Common Name Irloxacin
CAS Number 91524-15-1 Molecular Weight 300.28400
Density 1.36g/cm3 Boiling Point 495.9ºC at 760mmHg
Molecular Formula C16H13FN2O3 Melting Point N/A
MSDS N/A Flash Point 253.7ºC

 Use of Irloxacin


Irloxacin (Pirfloxacin) is a quinolone antibacterial agent. Irloxacin shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria. Orally active[1].

 Names

Name 1-ethyl-6-fluoro-4-oxo-7-pyrrol-1-ylquinoline-3-carboxylic acid
Synonym More Synonyms

 Irloxacin Biological Activity

Description Irloxacin (Pirfloxacin) is a quinolone antibacterial agent. Irloxacin shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria. Orally active[1].
Related Catalog
References

[1]. Casal M, et al. Preliminary study of the in vitro activity of irloxacin against mycobacteria. Chemotherapy. 1995;41(3):204-207.

[2]. Guzmán A, et al. Acute and subchronic toxicity studies of the new quinolone antibacterial agent irloxacin in rodents. Arzneimittelforschung. 1999;49(5):448-456.

 Chemical & Physical Properties

Density 1.36g/cm3
Boiling Point 495.9ºC at 760mmHg
Molecular Formula C16H13FN2O3
Molecular Weight 300.28400
Flash Point 253.7ºC
Exact Mass 300.09100
PSA 64.23000
LogP 2.64940
Index of Refraction 1.634
Storage condition -20°C

 Synthetic Route

 Synonyms

Irloxacin
1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)-3-quinolinecarboxylic acid
Pirfloxacin
Irloxacinum [Latin]
Irloxacino [Spanish]
pirflossacina
1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-pyrrolyl)-3-quinolinecarboxylic acid
6-fluoro-7-(1-pyrrolyl)-1-ethyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Irloxacine [French]
E-3432