Avoralstat

Modify Date: 2024-01-21 13:36:00

Avoralstat Structure
Avoralstat structure
Common Name Avoralstat
CAS Number 918407-35-9 Molecular Weight 513.544
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C28H27N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Avoralstat


Avoralstat is an oral plasma kallikrein (PKK) inhibitor, used for the treatment of hereditary angioedema.

 Names

Name AVORALSTAT
Synonym More Synonyms

 Avoralstat Biological Activity

Description Avoralstat is an oral plasma kallikrein (PKK) inhibitor, used for the treatment of hereditary angioedema.
Related Catalog
References

[1]. Aygoren-Pursun E, et al. Prophylaxis of hereditary angioedema attacks: A randomized trial of oral plasma kallikrein inhibition with avoralstat. J Allergy Clin Immunol. 2016 Sep;138(3):934-936.e5.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C28H27N5O5
Molecular Weight 513.544
Exact Mass 513.201233
LogP 0.80
Index of Refraction 1.673

 Synonyms

3-{2-[(4-Carbamimidoylphenyl)carbamoyl]-5-methoxy-4-vinylphenyl}-6-[(cyclopropylmethyl)carbamoyl]-2-pyridinecarboxylic acid
UNII-UX17773O15
AVORALSTAT
2-Pyridinecarboxylic acid, 3-[2-[[[4-[(Z)-aminoiminomethyl]phenyl]amino]carbonyl]-4-ethenyl-5-methoxyphenyl]-6-[[(cyclopropylmethyl)amino]carbonyl]-