Obafluorin

Modify Date: 2024-01-31 14:54:42

Obafluorin Structure
Obafluorin structure
Common Name Obafluorin
CAS Number 92121-68-1 Molecular Weight 358.30200
Density N/A Boiling Point N/A
Molecular Formula C17H14N2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Obafluorin


Obafluorin is a β-Lactone Antibiotic, that can be produced by Pseudomonas fluorescens ATCC 39502. Obafluorin exhibits antibacterial activity against a range of Gram-positive and Gram-negative bacteria. Obafluorin fully inhibits E. coli threonyl-tRNA synthetase[1].

 Names

Name 2,3-dihydroxy-N-[(2R,3S)-2-[(4-nitrophenyl)methyl]-4-oxooxetan-3-yl]benzamide
Synonym More Synonyms

 Obafluorin Biological Activity

Description Obafluorin is a β-Lactone Antibiotic, that can be produced by Pseudomonas fluorescens ATCC 39502. Obafluorin exhibits antibacterial activity against a range of Gram-positive and Gram-negative bacteria. Obafluorin fully inhibits E. coli threonyl-tRNA synthetase[1].
Related Catalog
References

[1]. Scott TA, et al. Immunity-Guided Identification of Threonyl-tRNA Synthetase as the Molecular Target of Obafluorin, a β-Lactone Antibiotic. ACS Chem Biol. 2019 Dec 20;14(12):2663-2671.  

 Chemical & Physical Properties

Molecular Formula C17H14N2O7
Molecular Weight 358.30200
Exact Mass 358.08000
PSA 145.17000
LogP 2.37050

 Synonyms

Obafluorin