N-(6-ACETYL-3-METHOXY-2-METHYLPHENYL)-4-(1-METHYLETHYL)-2-THIAZOLECARBOXAMIDE

Modify Date: 2024-01-09 17:03:30

N-(6-ACETYL-3-METHOXY-2-METHYLPHENYL)-4-(1-METHYLETHYL)-2-THIAZOLECARBOXAMIDE Structure
N-(6-ACETYL-3-METHOXY-2-METHYLPHENYL)-4-(1-METHYLETHYL)-2-THIAZOLECARBOXAMIDE structure
Common Name N-(6-ACETYL-3-METHOXY-2-METHYLPHENYL)-4-(1-METHYLETHYL)-2-THIAZOLECARBOXAMIDE
CAS Number 923289-20-7 Molecular Weight 332.41700
Density N/A Boiling Point N/A
Molecular Formula C17H20N2O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name N-(6-acetyl-3-methoxy-2-methylphenyl)-4-propan-2-yl-1,3-thiazole-2-carboxamide
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C17H20N2O3S
Molecular Weight 332.41700
Exact Mass 332.11900
PSA 100.02000
LogP 4.42240
Storage condition 2-8°C

 Synthetic Route

~89%

N-(6-ACETYL-3-METHOXY-2-METHYLPHENYL)-4-(1-METHYLETHYL)-2-THIAZOLECARBOXAMIDE Structure

N-(6-ACETYL-3-M...

CAS#:923289-20-7

Literature: TIBOTEC PHARMACEUTICALS LTD. Patent: WO2008/92954 A2, 2008 ; Location in patent: Page/Page column 29 ;

~41%

N-(6-ACETYL-3-METHOXY-2-METHYLPHENYL)-4-(1-METHYLETHYL)-2-THIAZOLECARBOXAMIDE Structure

N-(6-ACETYL-3-M...

CAS#:923289-20-7

Literature: Kazmierski, Wieslaw M.; Hamatake, Robert; Duan, Maosheng; Wright, Lois L.; Smith, Gary K.; Jarvest, Richard L.; Ji, Jing-Jing; Cooper, Joel P.; Tallant, Matthew D.; Crosby, Renae M.; Creech, Katrina; Wang, Amy; Li, Xianfeng; Zhang, Suoming; Zhang, Yong-Kang; Liu, Yang; Ding, Charles Z.; Zhou, Yasheen; Plattner, Jacob J.; Baker, Stephen J.; Bu, Wei; Liu, Liang Journal of Medicinal Chemistry, 2012 , vol. 55, # 7 p. 3021 - 3026

~93%

N-(6-ACETYL-3-METHOXY-2-METHYLPHENYL)-4-(1-METHYLETHYL)-2-THIAZOLECARBOXAMIDE Structure

N-(6-ACETYL-3-M...

CAS#:923289-20-7

Literature: InterMune, Inc. Patent: US2009/269305 A1, 2009 ;

~%

N-(6-ACETYL-3-METHOXY-2-METHYLPHENYL)-4-(1-METHYLETHYL)-2-THIAZOLECARBOXAMIDE Structure

N-(6-ACETYL-3-M...

CAS#:923289-20-7

Literature: Raboisson, Pierre; Lin, Tse-I; Kock, Herman de; Vendeville, Sandrine; Vreken, Wim Van de; McGowan, David; Tahri, Abdellah; Hu, Lili; Lenz, Oliver; Delouvroy, Frederic; Surleraux, Dominique; Wigerinck, Piet; Nilsson, Magnus; Rosenquist, Asa; Samuelsson, Bertil; Simmen, Kenneth Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 18 p. 5095 - 5100

~%

N-(6-ACETYL-3-METHOXY-2-METHYLPHENYL)-4-(1-METHYLETHYL)-2-THIAZOLECARBOXAMIDE Structure

N-(6-ACETYL-3-M...

CAS#:923289-20-7

Literature: Kazmierski, Wieslaw M.; Hamatake, Robert; Duan, Maosheng; Wright, Lois L.; Smith, Gary K.; Jarvest, Richard L.; Ji, Jing-Jing; Cooper, Joel P.; Tallant, Matthew D.; Crosby, Renae M.; Creech, Katrina; Wang, Amy; Li, Xianfeng; Zhang, Suoming; Zhang, Yong-Kang; Liu, Yang; Ding, Charles Z.; Zhou, Yasheen; Plattner, Jacob J.; Baker, Stephen J.; Bu, Wei; Liu, Liang Journal of Medicinal Chemistry, 2012 , vol. 55, # 7 p. 3021 - 3026

~%

N-(6-ACETYL-3-METHOXY-2-METHYLPHENYL)-4-(1-METHYLETHYL)-2-THIAZOLECARBOXAMIDE Structure

N-(6-ACETYL-3-M...

CAS#:923289-20-7

Literature: Kazmierski, Wieslaw M.; Hamatake, Robert; Duan, Maosheng; Wright, Lois L.; Smith, Gary K.; Jarvest, Richard L.; Ji, Jing-Jing; Cooper, Joel P.; Tallant, Matthew D.; Crosby, Renae M.; Creech, Katrina; Wang, Amy; Li, Xianfeng; Zhang, Suoming; Zhang, Yong-Kang; Liu, Yang; Ding, Charles Z.; Zhou, Yasheen; Plattner, Jacob J.; Baker, Stephen J.; Bu, Wei; Liu, Liang Journal of Medicinal Chemistry, 2012 , vol. 55, # 7 p. 3021 - 3026

~%

N-(6-ACETYL-3-METHOXY-2-METHYLPHENYL)-4-(1-METHYLETHYL)-2-THIAZOLECARBOXAMIDE Structure

N-(6-ACETYL-3-M...

CAS#:923289-20-7

Literature: Kazmierski, Wieslaw M.; Hamatake, Robert; Duan, Maosheng; Wright, Lois L.; Smith, Gary K.; Jarvest, Richard L.; Ji, Jing-Jing; Cooper, Joel P.; Tallant, Matthew D.; Crosby, Renae M.; Creech, Katrina; Wang, Amy; Li, Xianfeng; Zhang, Suoming; Zhang, Yong-Kang; Liu, Yang; Ding, Charles Z.; Zhou, Yasheen; Plattner, Jacob J.; Baker, Stephen J.; Bu, Wei; Liu, Liang Journal of Medicinal Chemistry, 2012 , vol. 55, # 7 p. 3021 - 3026

 Synonyms

2-Thiazolecarboxamide,N-(6-acetyl-3-methoxy-2-methylphenyl)-4-(1-methylethyl)
THI053
N-(6-acetyl-3-methoxy-2-methylphenyl)-4-isopropylthiazole-2-carboxamide
N-[6-acetyl-2-methyl-3-(methyloxy)phenyl]-4-(1-methylethyl)-1,3-thiazole-2-carboxamide
N-(6-acetyl-2-methyl-3-methoxyphenyl)-4-isopropylthiazole-2-carboxamide
N-(6-acetyl-3-methoxy-2-methylphenyl)-4-(1-methylethyl)-2-Thiazolecarboxamide
2'-(4-isopropylthiazol-2-ylcarbonylamino)-4'-methoxy-3'-methylacetophenone
1-acetyl-2-[(4-isopropyl-thiazol-2-yl)-carbonylamino]-3-methyl-4-methoxy-benzene
2'-[[(4-iso-propylthiazole-2-yl)(oxo)methyl]amino]-4'-methoxy-3'-methylacetophenone