HG106

Modify Date: 2024-04-06 21:56:47

HG106 Structure
HG106 structure
Common Name HG106
CAS Number 928712-10-1 Molecular Weight 316.74
Density N/A Boiling Point N/A
Molecular Formula C15H13ClN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HG106


HG106 is a potent SLC7A11 inhibitor. HG106 markedly decreased cystine uptake and intracellular glutathione biosynthesis. HG106 can be used for the research of KRAS-mutant lung adenocarcinoma[1].

 Names

Name Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]-

 HG106 Biological Activity

Description HG106 is a potent SLC7A11 inhibitor. HG106 markedly decreased cystine uptake and intracellular glutathione biosynthesis. HG106 can be used for the research of KRAS-mutant lung adenocarcinoma[1].
Related Catalog
References

[1]. Hu K, et al. Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma. J Clin Invest. 2020 Apr 1;130(4):1752-1766.  

 Chemical & Physical Properties

Molecular Formula C15H13ClN4O2
Molecular Weight 316.74
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.