1-(4-Thio-beta-D-ribofuranosyl)cytosine

Modify Date: 2024-01-10 19:06:40

1-(4-Thio-beta-D-ribofuranosyl)cytosine Structure
1-(4-Thio-beta-D-ribofuranosyl)cytosine structure
Common Name 1-(4-Thio-beta-D-ribofuranosyl)cytosine
CAS Number 93080-09-2 Molecular Weight 259.28
Density N/A Boiling Point N/A
Molecular Formula C9H13N3O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1-(4-Thio-beta-D-ribofuranosyl)cytosine


4′-Thiocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-(4-thio-β-D-ribofuranosyl)-cytosine
Synonym More Synonyms

 1-(4-Thio-beta-D-ribofuranosyl)cytosine Biological Activity

Description 4′-Thiocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C9H13N3O4S
Molecular Weight 259.28
Exact Mass 259.06300
PSA 146.90000

 Synonyms

4'-thio-cytidine
4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-thiophen-2-yl)-1H-pyrimidin-2-one
4'-Thio-β-D-ribofuranosylcytosin
1-(4-thio-β-D-ribofuranosyl)cytosine
1-<4-Thio-β-D-ribofuranosyl>-cytosin
4'-thiocytidine
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