Pexopiprant

Modify Date: 2023-01-11 17:27:39

Pexopiprant Structure
Pexopiprant structure
Common Name Pexopiprant
CAS Number 932708-14-0 Molecular Weight 456.27
Density 1.4±0.1 g/cm3 Boiling Point 539.5±45.0 °C at 760 mmHg
Molecular Formula C21H17Cl2F2NO4 Melting Point N/A
MSDS N/A Flash Point 280.1±28.7 °C

 Use of Pexopiprant


Pexopiprant is an oral antagonist of the prostaglandin D2 receptor 2 (DP2),Ki < 100nM. Pexopiprant can be used in studies of asthma[1].

 Names

Name {[8-Chloro-3-(4-chlorobenzyl)-4-(difluoromethoxy)-2-ethyl-5-quinolinyl]oxy}acetic acid
Synonym More Synonyms

 Pexopiprant Biological Activity

Description Pexopiprant is an oral antagonist of the prostaglandin D2 receptor 2 (DP2),Ki < 100nM. Pexopiprant can be used in studies of asthma[1].
Related Catalog
Target

hDP2:<100 nM (Ki)

References

[1]. Cramp, Michael Colin; Arienzo, Rosa; Hynd, George; Crackett, Peter; Griffon, Yann; Harrison, Trevor Keith; Ray, Nicholas Charles; Finch, Harry; Montana, John Gary.Preparation of quinoline derivatives as CRTH2 antagonists. WO2007036743 A2.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 539.5±45.0 °C at 760 mmHg
Molecular Formula C21H17Cl2F2NO4
Molecular Weight 456.27
Flash Point 280.1±28.7 °C
Exact Mass 455.050262
LogP 6.04
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.601

 Synonyms

{[8-Chloro-3-(4-chlorobenzyl)-4-(difluoromethoxy)-2-ethyl-5-quinolinyl]oxy}acetic acid
Acetic acid, 2-[[8-chloro-3-[(4-chlorophenyl)methyl]-4-(difluoromethoxy)-2-ethyl-5-quinolinyl]oxy]-
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