(10-BRomodecyl)phosphonic acid

Modify Date: 2024-01-16 19:20:02

(10-BRomodecyl)phosphonic acid Structure
(10-BRomodecyl)phosphonic acid structure
Common Name (10-BRomodecyl)phosphonic acid
CAS Number 934985-98-5 Molecular Weight 301.16
Density N/A Boiling Point N/A
Molecular Formula C10H22BrO3P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (10-BRomodecyl)phosphonic acid


(10-BRomodecyl)phosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name (10-BRomodecyl)phosphonic acid
Synonym More Synonyms

 (10-BRomodecyl)phosphonic acid Biological Activity

Description (10-BRomodecyl)phosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H22BrO3P
Molecular Weight 301.16

 Synonyms

MFCD25424105