Ceftolozane sulfate

Ceftolozane sulfate Structure
Ceftolozane sulfate structure
Common Name Ceftolozane sulfate
CAS Number 936111-69-2 Molecular Weight 764.77
Density N/A Boiling Point N/A
Molecular Formula C23H32N12O12S3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ceftolozane sulfate


Ceftolozane (CXA-101) sulfate is an antipseudomonal cephalosporin. Ceftolozane sulfate inhibits P. aeruginosa PAO1 with an MIC of 0.5 μg/mL. Ceftolozane sulfate can also inhibit β-lactam-resistant P. aeruginosa[1][2].

 Names

Name Ceftolozane sulfate

 Ceftolozane sulfate Biological Activity

Description Ceftolozane (CXA-101) sulfate is an antipseudomonal cephalosporin. Ceftolozane sulfate inhibits P. aeruginosa PAO1 with an MIC of 0.5 μg/mL. Ceftolozane sulfate can also inhibit β-lactam-resistant P. aeruginosa[1][2].
Related Catalog
Target

MIC: 0.5 μg/mL (P. aeruginosa PAO1)[1]

References

[1]. Moyá B, et al. Affinity of the new cephalosporin CXA-101 to penicillin-binding proteins of Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2010 Sep;54(9):3933-7.  

[2]. Moya B, et al. Activity of a new cephalosporin, CXA-101 (FR264205), against beta-lactam-resistant Pseudomonas aeruginosa mutants selected in vitro and after antipseudomonal treatment of intensive care unit patients. Antimicrob Agents Chemother. 2010 Mar;54(3):1213-7.  

 Chemical & Physical Properties

Molecular Formula C23H32N12O12S3
Molecular Weight 764.77
InChIKey UJDQGRLTPBVSFN-TVNHLQOTSA-N
SMILES Cn1c(N)c(NC(=O)NCCN)c[n+]1CC1=C(C(=O)O)N2C(=O)C(NC(=O)C(=NOC(C)(C)C(=O)O)c3nsc(N)n3)C2SC1.O=S(=O)([O-])O
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