3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-5-[(4-propylpiperazin-1-yl)methyl]-1,3-oxazolidin-2-one

Modify Date: 2022-04-22 17:52:10

3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-5-[(4-propylpiperazin-1-yl)methyl]-1,3-oxazolidin-2-one structure	Common Name	3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-5-[(4-propylpiperazin-1-yl)methyl]-1,3-oxazolidin-2-one
	CAS Number	94374-28-4	Molecular Weight	365.38400
	Density	1.42g/cm3	Boiling Point	488.4ºC at 760mmHg
	Molecular Formula	C₁₆H₂₃N₅O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	249.2ºC

Name	3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-5-[(4-propylpiperazin-1-yl)methyl]-1,3-oxazolidin-2-one
Synonym	More Synonyms

Density	1.42g/cm3
Boiling Point	488.4ºC at 760mmHg
Molecular Formula	C₁₆H₂₃N₅O₅
Molecular Weight	365.38400
Flash Point	249.2ºC
Exact Mass	365.17000
PSA	107.34000
LogP	1.70700
Index of Refraction	1.642

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RQ3677000

CHEMICAL NAME :: 2-Oxazolidinone, 3-((5-nitro-2-furfurylidene)amino)-5-((4-propyl-1-pip erazinyl)methyl)-

CAS REGISTRY NUMBER :: 94374-28-4

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C16-H23-N5-O5

MOLECULAR WEIGHT :: 365.44

WISWESSER LINE NOTATION :: T6N DNTJ A3 D1- DT5NVOTJ ANU1- BT5OJ ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 19,269,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 19,269,1964

5-Nitrofuraldehyde

CAS#:698-63-5

N/A

CAS#:91346-54-2

Ethyl carbonate

CAS#:105-58-8

3-[(E)-(5-nitro...

CAS#:94374-28-4

Literature: Failla,L. et al. Farmaco, Edizione Scientifica, 1964 , vol. 19, p. 269 - 285

Precursor 2
CAS#:698-63-5 5-Nitrofuraldehyde CAS#:105-58-8 Ethyl carbonate
DownStream 0

PM 365

3-<5-Nitro-furfurylidenamino>-5-<4-propyl-piperazinomethyl>-oxazolid-2-on

Dichloromethane
CAS#:75-09-2

Polyacrylic acid
CAS#:9003-01-4

sodium carbonate
CAS#:497-19-8

Silicon dioxide
CAS#:7631-86-9

Triethanolamine
CAS#:102-71-6

Demeton
CAS#:126-75-0

Water
CAS#:7732-18-5

4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9

Diclofenac sodium
CAS#:15307-79-6

Budesonide
CAS#:51372-29-3

3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-5-[(4-propylpiperazin-1-yl)methyl]-1,3-oxazolidin-2-one

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Precursor & DownStream

Synonyms