Quinagolide (hydrochloride)

Modify Date: 2024-01-11 03:50:44

Quinagolide (hydrochloride) Structure
Quinagolide (hydrochloride) structure
Common Name Quinagolide (hydrochloride)
CAS Number 94424-50-7 Molecular Weight 432.02000
Density N/A Boiling Point 539.1ºC at 760 mmHg
Molecular Formula C20H34ClN3O3S Melting Point N/A
MSDS N/A Flash Point 279.8ºC

 Use of Quinagolide (hydrochloride)


Quinagolide hydrochloride is a selective dopamine D2 receptor agonist, also is a prolactin inhibitor. Target: dopamine D2 receptor, prolactinQuinagolide is a selective, D2 receptor agonist (or prolactin-release inhibitor) that is used for the treatment of elevated levels of prolactin. Quinagolide is helpful in reducing prolactin levels to reduce milk production for certain medical reasons and to treat some types of infertility, breast problems and menstrual disorders. Quinagolide exerts a strong and specific inhibitory effect on prolactin release by acting directly on the prolactin-secreting cells of the anterior pituitary without reducing the levels of other pituitary hormones.

 Names

Name (3S,4aS,10aR)-3-(diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline,hydrochloride
Synonym More Synonyms

 Quinagolide (hydrochloride) Biological Activity

Description Quinagolide hydrochloride is a selective dopamine D2 receptor agonist, also is a prolactin inhibitor. Target: dopamine D2 receptor, prolactinQuinagolide is a selective, D2 receptor agonist (or prolactin-release inhibitor) that is used for the treatment of elevated levels of prolactin. Quinagolide is helpful in reducing prolactin levels to reduce milk production for certain medical reasons and to treat some types of infertility, breast problems and menstrual disorders. Quinagolide exerts a strong and specific inhibitory effect on prolactin release by acting directly on the prolactin-secreting cells of the anterior pituitary without reducing the levels of other pituitary hormones.
Related Catalog
References

[1]. Mostafa AA, et al. Spectrophotometric determination of clobetasol propionate, halobetasol propionate, quinagolide hydrochloride, through charge transfer complexation. J Pharm Biomed Anal. 2002 Mar 1;27(6):889-899.

 Chemical & Physical Properties

Boiling Point 539.1ºC at 760 mmHg
Molecular Formula C20H34ClN3O3S
Molecular Weight 432.02000
Flash Point 279.8ºC
Exact Mass 431.20100
PSA 81.26000
LogP 4.34770
Storage condition 2-8℃

 Synonyms

Quinagolide HCl
Quinagolide hydrochloride
Norprolac
Quinagolide hydrochloride (BAN)
Norprolac (TN)
Quinagolide (hydrochloride)
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