Ramucirumab

Modify Date: 2024-01-03 10:24:09

Ramucirumab Structure
Ramucirumab structure
Common Name Ramucirumab
CAS Number 947687-13-0 Molecular Weight 6369.07
Density N/A Boiling Point N/A
Molecular Formula C285H434N74O88S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ramucirumab


Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors[1]. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D[2].

 Names

Name Ramucirumab

 Ramucirumab Biological Activity

Description Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors[1]. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D[2].
Related Catalog
Target

VEGFR-2

References

[1]. Fala L. Cyramza (Ramucirumab) Approved for the Treatment of Advanced Gastric Cancer and Metastatic Non-Small-Cell Lung Cancer. Am Health Drug Benefits. 2015 Mar;8(Spec Feature):49-53.

[2]. Oholendt AL, et al. Ramucirumab: A New Therapy for Advanced Gastric Cancer. J Adv Pract Oncol. 2015 Jan-Feb;6(1):71-5.

 Chemical & Physical Properties

Molecular Formula C285H434N74O88S2
Molecular Weight 6369.07
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.