B-Raf IN 1
Modify Date: 2024-01-05 11:29:22
B-Raf IN 1 structure
|
Common Name | B-Raf IN 1 | ||
|---|---|---|---|---|
| CAS Number | 950736-05-7 | Molecular Weight | 515.529 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C29H24F3N5O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of B-Raf IN 1B-Raf IN 1 is a potent and selective B-Raf kinase inhibitor with an IC50 of 24 nM. |
| Name | Benzamide, N-[3-[3-[4-[(dimethylamino)methyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl) |
|---|---|
| Synonym | More Synonyms |
| Description | B-Raf IN 1 is a potent and selective B-Raf kinase inhibitor with an IC50 of 24 nM. |
|---|---|
| Related Catalog | |
| Target |
B-Raf:24 nM (IC50) |
| In Vitro | B-Raf IN 1 (Compound 10n) inhibits WM 266-4 and HT29 cells with IC50s of 0.92 and 0.78 μM, respectively[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C29H24F3N5O |
| Molecular Weight | 515.529 |
| Exact Mass | 515.193298 |
| PSA | 62.53000 |
| LogP | 4.39 |
| Appearance of Characters | yellow solid |
| Index of Refraction | 1.621 |
| Storage condition | -20℃ |
| N-[3-(3-{4-[(Dimethylamino)methyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide |
| Benzamide, N-[3-[3-[4-[(dimethylamino)methyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)- |
| B-Raf IN 1 |