TP748

Modify Date: 2024-01-09 21:10:07

TP748 Structure
TP748 structure
Common Name TP748
CAS Number 951698-15-0 Molecular Weight 258.316
Density 1.1±0.1 g/cm3 Boiling Point 367.3±42.0 °C at 760 mmHg
Molecular Formula C15H18N2O2 Melting Point N/A
MSDS N/A Flash Point 176.0±27.9 °C

 Use of TP748


TP748,an isoxazole, is a key intermediate for fully synthetic tetracyclines[1].

 Names

Name (S)-1-(3-(benzyloxy)isoxazol-5-yl)-N,N-dimethylprop-2-en-1-amine
Synonym More Synonyms

 TP748 Biological Activity

Description TP748,an isoxazole, is a key intermediate for fully synthetic tetracyclines[1].
Related Catalog
In Vitro A robust, cost effective and high yielding manufacturing process for enantiomerically enriched (S)-allylic amine 3, a key intermediate for fully synthetic tetracyclines have been developed[1].
References

[1]. Wu-Yan Zhang, et al. Process Research and Development of TP-808: A Key Intermediate for the Manufacture of Synthetic Tetracyclines. Process Res. Dev. 2017, 21, 3, 377-386.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 367.3±42.0 °C at 760 mmHg
Molecular Formula C15H18N2O2
Molecular Weight 258.316
Flash Point 176.0±27.9 °C
Exact Mass 258.136841
PSA 38.50000
LogP 2.95
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.547
Storage condition -20°C

 Synonyms

5-Isoxazolemethanamine, α-ethenyl-N,N-dimethyl-3-(phenylmethoxy)-, (αS)-
(1S)-1-[3-(Benzyloxy)-1,2-oxazol-5-yl]-N,N-dimethyl-2-propen-1-amine
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