CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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UQ2282000
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CHEMICAL NAME :
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Pyrazinecarboxamide, N-(morpholinomethyl)-
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CAS REGISTRY NUMBER :
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952-54-5
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LAST UPDATED :
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199707
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DATA ITEMS CITED :
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2
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MOLECULAR FORMULA :
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C10-H14-N4-O2
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MOLECULAR WEIGHT :
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222.28
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WISWESSER LINE NOTATION :
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T6N DOTJ A1MV- BT6N DNJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Human - woman
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DOSE/DURATION :
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3360 mg/kg/17W-I
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TOXIC EFFECTS :
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Liver - hepatitis (hepatocellular necrosis), diffuse
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REFERENCE :
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JOHEEC Journal of Hepathology. (Elsevier Science, 655 Avenue of the Americas, New York, NY 10010) V.1- 1985- Volume(issue)/page/year: 25,1001,1996
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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2750 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 5,39,1962
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