Niga-ichigoside F1
Modify Date: 2024-01-03 17:06:16
Niga-ichigoside F1 structure
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Common Name | Niga-ichigoside F1 | ||
|---|---|---|---|---|
| CAS Number | 95262-48-9 | Molecular Weight | 666.839 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 775.0±60.0 °C at 760 mmHg | |
| Molecular Formula | C36H58O11 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 234.7±26.4 °C | |
Use of Niga-ichigoside F1Niga-ichigoside F1, an orally active ursane triterpenoid, has antihyperlipidemic and antioxidant activities. Niga-ichigoside F1 can prevent high-fat diet (HFD)-induced hepatic steatosis[1]. |
| Name | Niga-ichigoside F1 |
|---|---|
| Synonym | More Synonyms |
| Description | Niga-ichigoside F1, an orally active ursane triterpenoid, has antihyperlipidemic and antioxidant activities. Niga-ichigoside F1 can prevent high-fat diet (HFD)-induced hepatic steatosis[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Niga-ichigoside F1 (2.5, 5, 10, 20 μM; for 24 hours) inhibits lipid accumu-lation in free fatty acid (FFA)-treated HepG2 cells in a dose-dependent manner. Niga-ichigoside F1 has no effects on cell viability[1]. Both nuclear and cytoplasmic Nrf2 expressions are lowered in Con, Niga-ichigoside F1 (20 μM), FFA (1 mM), and Niga-ichigoside F1 plus FFA treated Nrf2-silenced cells[1]. |
| In Vivo | Niga-ichigoside F1 (40 mg/kg; oral gavage; for 12 weeks) alleviates hepatic steatosis, possibly by significantly interacting with high-fat diet (HFD) to regulate lipid metabolism genes (including Srebp1c, Acc1, Fasn, Scd1, Cpt1a and Fabp5) in four-week-old male C57BL/6J mice[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 775.0±60.0 °C at 760 mmHg |
| Molecular Formula | C36H58O11 |
| Molecular Weight | 666.839 |
| Flash Point | 234.7±26.4 °C |
| Exact Mass | 666.397888 |
| LogP | 3.84 |
| Vapour Pressure | 0.0±6.0 mmHg at 25°C |
| Index of Refraction | 1.616 |
| Storage condition | 2-8℃ |
| 1-O-[(2α,3β)-2,3,19,23-Tetrahydroxy-28-oxours-12-en-28-yl]-β-D-glucopyranose |
| 19α-hydroxyasiatic acid-28-O-β-D-glucopyrannoside |
| β-D-Glucopyranose, 1-O-[(2α,3β)-2,3,19,23-tetrahydroxy-28-oxours-12-en-28-yl]- |