10Panx
Modify Date: 2025-09-25 19:00:23
10Panx structure
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Common Name | 10Panx | ||
|---|---|---|---|---|
| CAS Number | 955091-53-9 | Molecular Weight | 1242.34 | |
| Density | 1.48±0.1 g/cm3 (20 °C, 760 mmHg) | Boiling Point | N/A | |
| Molecular Formula | C58H79N15O16 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 10Panx10Panx is a biological active peptide. (This is a Pannexin-1 (Panx1) mimetic blocking peptide. Pannexin-1 is a recently identified membrane protein that can form gap junction-like connections allowing intercellular passage of dyes when overexpressed in two adjacent oocytes or mammalian epithelial cell lines. Blockade of pannexin-1 in macrophage endogenously expressing the ATP-gated P2X7 receptor (P2X7R) blocks the initial dye uptake, but not the ionic current, and also blocks processing and release of interleukin-1b (IL-1b) in response to P2X7R activation.) |
| Name | L-Tyrosine, L-tryptophyl-L-arginyl-L-glutaminyl-L-alanyl-L-alanyl-L-phenylalanyl-L-valyl-L-α-aspartyl-L-seryl |
|---|---|
| Synonym | More Synonyms |
| Description | 10Panx is a biological active peptide. (This is a Pannexin-1 (Panx1) mimetic blocking peptide. Pannexin-1 is a recently identified membrane protein that can form gap junction-like connections allowing intercellular passage of dyes when overexpressed in two adjacent oocytes or mammalian epithelial cell lines. Blockade of pannexin-1 in macrophage endogenously expressing the ATP-gated P2X7 receptor (P2X7R) blocks the initial dye uptake, but not the ionic current, and also blocks processing and release of interleukin-1b (IL-1b) in response to P2X7R activation.) |
|---|---|
| Related Catalog |
| Density | 1.48±0.1 g/cm3 (20 °C, 760 mmHg) |
|---|---|
| Molecular Formula | C58H79N15O16 |
| Molecular Weight | 1242.34 |
| Exact Mass | 1241.58000 |
| PSA | 523.76000 |
| LogP | 2.47770 |
| InChIKey | JCJASTVQGSKHKZ-QZHJRRRASA-N |
| SMILES | CC(NC(=O)C(C)NC(=O)C(CCC(N)=O)NC(=O)C(CCCN=C(N)N)NC(=O)C(N)Cc1c[nH]c2ccccc12)C(=O)NC(Cc1ccccc1)C(=O)NC(C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)O)C(C)C |
| Storage condition | -20°C |
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