![]() HBF-0259 structure
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Common Name | HBF-0259 | ||
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CAS Number | 957011-15-3 | Molecular Weight | 364.20 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C16H12Cl2FN5 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of HBF-0259HBF-0259 is a potent and selective inhibitor of hepatitis B virus (HBV) surface antigen (HBsAg) secretion, with an EC50 of 1.5 μM in HepG2.2.15 cells. HBF-0259 has no effect on HBV DNA synthesis[1][2]. |
Name | HBF-0259 |
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Description | HBF-0259 is a potent and selective inhibitor of hepatitis B virus (HBV) surface antigen (HBsAg) secretion, with an EC50 of 1.5 μM in HepG2.2.15 cells. HBF-0259 has no effect on HBV DNA synthesis[1][2]. |
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Related Catalog | |
In Vitro | HBF-0259 (0.0158-50.0 μM) inhibits the HBsAg secretion (EC50=1.5 μM) in HepDE19 cells, with an CC50 of >50 μM[1]. HBF-0259 (2-8 μM) significantly reduces the abundance of both L and M in the supernatants of HepG2.2.15 cells[1]. |
References |
Molecular Formula | C16H12Cl2FN5 |
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Molecular Weight | 364.20 |