CBS1117

Modify Date: 2024-01-17 21:50:54

CBS1117 Structure
CBS1117 structure
Common Name CBS1117
CAS Number 959245-08-0 Molecular Weight 315.24
Density N/A Boiling Point N/A
Molecular Formula C15H20Cl2N2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CBS1117


CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A viruses, A/Puerto Rico/8/34 (H1N1). CBS1117 interferes with the hemagglutinin (HA)-mediated fusion process[1].

 Names

Name CBS1117

 CBS1117 Biological Activity

Description CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A viruses, A/Puerto Rico/8/34 (H1N1). CBS1117 interferes with the hemagglutinin (HA)-mediated fusion process[1].
Related Catalog
Target

IC50: 70 nM (H1N1)[1]

In Vitro CBS1117 has a lower IC50 value of 70 nM and higher CC50 value of 274 μM, leading to an excellent antiviral selectivity index value (SI value of 3914) in human lung epithelial cell line (A549)[1].
References

[1]. Hussein AFA, et al. Identification of entry inhibitors with 4-aminopiperidine scaffold targeting group 1 influenza A virus. Antiviral Res. 2020 May;177:104782.

 Chemical & Physical Properties

Molecular Formula C15H20Cl2N2O
Molecular Weight 315.24
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