8-Aza-7-bromo-7-deazaguanosine

Modify Date: 2025-09-10 22:55:59

8-Aza-7-bromo-7-deazaguanosine Structure
8-Aza-7-bromo-7-deazaguanosine structure
Common Name 8-Aza-7-bromo-7-deazaguanosine
CAS Number 96555-37-2 Molecular Weight 362.14
Density N/A Boiling Point N/A
Molecular Formula C10H12BrN5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 8-Aza-7-bromo-7-deazaguanosine


8-Aza-7-bromo-7-deazaguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 6-amino-3-bromo-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2H-pyrazolo[3,4-d]pyrimidin-4-one

 8-Aza-7-bromo-7-deazaguanosine Biological Activity

Description 8-Aza-7-bromo-7-deazaguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C10H12BrN5O5
Molecular Weight 362.14
Exact Mass 361.00200
PSA 160.50000

 8-Aza-7-bromo-7-deazaguanosineBioassay

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Name: HIV Cellular Data
Source: NIAID
Target: N/A
External Id: HIV Cellular Data
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