Tanshindiol B

Modify Date: 2024-01-13 19:41:14

Tanshindiol B Structure
Tanshindiol B structure
Common Name Tanshindiol B
CAS Number 97465-70-8 Molecular Weight 312.31700
Density 1.436±0.06 g/cm3(20 °C , 760mmHg) Boiling Point 561.5±50.0 °C (760 mmHg)
Molecular Formula C18H16O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tanshindiol B


Tanshindiol B, a naphthaquinone diterpene, inhibits GBM growth by induction of noptosis (NQO1-dependent necrosis)[1].

 Names

Name Phenanthro[1,2-b]furan-10,11-dione, 6,7,8,9-tetrahydro-6,7-dihydroxy-1,6-dimethyl-, (6R,7S)-
Synonym More Synonyms

 Tanshindiol B Biological Activity

Description Tanshindiol B, a naphthaquinone diterpene, inhibits GBM growth by induction of noptosis (NQO1-dependent necrosis)[1].
Related Catalog
In Vitro Tanshindiol B (TSB) 触发明显的细胞死亡,不属于凋亡,而是氧化应激引起的坏死。
References

[1]. A Yagi, et al. Effect of abietane- type pigments from Salvia miltiorrhiza on post-hypoxic recovery of cardiac contractile force in rats. Planta Med. 1991 Jun;57(3):288-9.  

 Chemical & Physical Properties

Density 1.436±0.06 g/cm3(20 °C , 760mmHg)
Boiling Point 561.5±50.0 °C (760 mmHg)
Molecular Formula C18H16O5
Molecular Weight 312.31700
Exact Mass 312.10000
PSA 87.74000
LogP 2.14860

 Synonyms

Tanshindiol B
Phenanthro[1,2-b]furan-10,11-dione, 6,7,8,9-tetrahydro-6,7-dihydroxy-1,6-dimethyl-, (6R-cis)-
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