Zedoarondiol
Modify Date: 2024-01-02 05:10:04
Zedoarondiol structure
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Common Name | Zedoarondiol | ||
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| CAS Number | 98644-24-7 | Molecular Weight | 252.35 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 396.8±42.0 °C at 760 mmHg | |
| Molecular Formula | C15H24O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 207.9±24.4 °C | |
Use of ZedoarondiolZedoarondiol, a sesquiterpene lactone compound, with antioxidant and anti-inflammatory activity. Zedoarondiol can be used for atherosclerosis research[1][2]. |
| Name | Zedoarondiol |
|---|---|
| Synonym | More Synonyms |
| Description | Zedoarondiol, a sesquiterpene lactone compound, with antioxidant and anti-inflammatory activity. Zedoarondiol can be used for atherosclerosis research[1][2]. |
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| Related Catalog | |
| In Vitro | Zedoarondiol (5-20 μg/mL) attenuates HUVECs injury, up-regulated SOD activity, suppressed formation of MDA and ROS, and secretion and protein expression of IL-1β, TNF-α, and MCP-1 in injured HUVECs induced by oxidized low-density lipoprotein (ox-LDL)[1]. Zedoarondiol induces nuclear Nrf2 translocation from cytoplasm into nucleus and up-regulated expression of HO-1, NQO1, and Nrf2 in nucleus[1]. Zedoarondiol suppresses PDGF-BB-induced vascular smooth muscle cells (VSMCs) proliferation and DNA synthesis, and induces cell cycle arrest in G0/G1 phase. In addition, Zedoarondiol activates AMPK and ACC, inhibited the phosphorylation of mTOR and p70S6K, increases the expression of p53 and p21, and decreases the expression of CDK2 and cyclin E[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 396.8±42.0 °C at 760 mmHg |
| Molecular Formula | C15H24O3 |
| Molecular Weight | 252.35 |
| Flash Point | 207.9±24.4 °C |
| Exact Mass | 252.172546 |
| LogP | 1.63 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.529 |
| ZEDOARONDIOL |