Kushenol E

Modify Date: 2024-01-02 21:15:59

Kushenol E Structure
Kushenol E structure
 Common Name Kushenol E
CAS Number 99119-72-9 Molecular Weight 424.486
Density 1.3±0.1 g/cm3 Boiling Point 674.8±55.0 °C at 760 mmHg
Molecular Formula C25H28O6 Melting Point N/A
MSDS N/A Flash Point 230.7±25.0 °C

 Use of Kushenol E


Kushenol E is a class of flavonoids isolated from Sophora flavescens and is a non-competitive indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC50 of 7.7 µM and a Ki of 9.5 µM, has anti-tumor activity[1].

 Names

Name Kushenol E
Synonym More Synonyms

 Kushenol E Biological Activity

Description Kushenol E is a class of flavonoids isolated from Sophora flavescens and is a non-competitive indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC50 of 7.7 µM and a Ki of 9.5 µM, has anti-tumor activity[1].
Related Catalog
References

[1]. Kwon M, et al. Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity. J Enzyme Inhib Med Chem. 2019 Dec;34(1):1481-1488.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 674.8±55.0 °C at 760 mmHg
Molecular Formula C25H28O6
Molecular Weight 424.486
Flash Point 230.7±25.0 °C
Exact Mass 424.188599
LogP 6.66
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.632

 Synonyms

4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-6,8-bis(3-methyl-2-buten-1-yl)-, (2S)-
(2S)-2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-6,8-bis(3-methyl-2-buten-1-yl)-2,3-dihydro-4H-chromen-4-one
4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-6,8-bis(3-methyl-2-butenyl)-, (S)-
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Chemsrc provides Kushenol E(CAS#:99119-72-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Kushenol E are included as well.>> amp version: Kushenol E

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