5,6,7,8-tetrahydro-1H-[1,2,4]triazolo[5,1-b]quinazolin-9-one

Modify Date: 2025-08-25 12:59:45

5,6,7,8-tetrahydro-1H-[1,2,4]triazolo[5,1-b]quinazolin-9-one Structure
5,6,7,8-tetrahydro-1H-[1,2,4]triazolo[5,1-b]quinazolin-9-one structure
Common Name 5,6,7,8-tetrahydro-1H-[1,2,4]triazolo[5,1-b]quinazolin-9-one
CAS Number 99131-44-9 Molecular Weight 190.20200
Density N/A Boiling Point N/A
Molecular Formula C9H10N4O Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 5,6,7,8-tetrahydro-1H-[1,2,4]triazolo[5,1-b]quinazolin-9-one
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C9H10N4O
Molecular Weight 190.20200
Exact Mass 190.08500
PSA 63.05000
LogP 0.29640
InChIKey VTDUUMAZYOEHOL-UHFFFAOYSA-N
SMILES O=c1c2c(nc3nc[nH]n13)CCCC2

 Synthetic Route

~80%

5,6,7,8-tetrahydro-1H-[1,2,4]triazolo[5,1-b]quinazolin-9-one Structure

5,6,7,8-tetrahy...

CAS#:99131-44-9

Literature: Ram, Vishnu J. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 825 - 829

~%

5,6,7,8-tetrahydro-1H-[1,2,4]triazolo[5,1-b]quinazolin-9-one Structure

5,6,7,8-tetrahy...

CAS#:99131-44-9

Literature: Hlavka, Joseph J.; Bitha, Panayota; Lin, Yang-i; Strohmeyer, Timothy Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1317 - 1322

 Bioassay

View more

Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
Name: AlphaScreen-based biochemical high throughput primary assay to identify activators of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: FBW7_ACT_ALPHA_1536_1X%ACT PRUN
Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN
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 Synonyms

5,6,7,8-Tetrahydro[1,2,4]triazolo[5,1-b]quinazolin-9(4H)-one
5,6,7,8-Tetrahydro-4H-[1,2,4]triazolo[5,1-b]quinazolin-9-one
7-hydroxy-5,6-tetrametheno-[1,2,4]triazolo[1,5-a]pyrimidine
[1,2,4]Triazolo[5,1-b]quinazolin-9-ol,5,6,7,8-tetrahydro
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