Alkynyl Palmitic Acid

Modify Date: 2024-01-02 16:53:11

Alkynyl Palmitic Acid Structure
Alkynyl Palmitic Acid structure
Common Name Alkynyl Palmitic Acid
CAS Number 99208-90-9 Molecular Weight 252.392
Density 0.9±0.1 g/cm3 Boiling Point 371.8±15.0 °C at 760 mmHg
Molecular Formula C16H28O2 Melting Point N/A
MSDS N/A Flash Point 180.7±15.1 °C

 Use of Alkynyl Palmitic Acid


Alkynyl Palmitic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name hexadec-15-ynoic acid
Synonym More Synonyms

 Alkynyl Palmitic Acid Biological Activity

Description Alkynyl Palmitic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 371.8±15.0 °C at 760 mmHg
Molecular Formula C16H28O2
Molecular Weight 252.392
Flash Point 180.7±15.1 °C
Exact Mass 252.208923
PSA 37.30000
LogP 5.80
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.470

 Safety Information

HS Code 2916190090

 Synthetic Route

~88%

Alkynyl Palmitic Acid Structure

Alkynyl Palmiti...

CAS#:99208-90-9

Literature: Menger; Chen; Brocchini; Hopkins; Hamilton Journal of the American Chemical Society, 1993 , vol. 115, # 15 p. 6600 - 6608

~%

Alkynyl Palmitic Acid Structure

Alkynyl Palmiti...

CAS#:99208-90-9

Literature: Menger; Chen; Brocchini; Hopkins; Hamilton Journal of the American Chemical Society, 1993 , vol. 115, # 15 p. 6600 - 6608

~%

Alkynyl Palmitic Acid Structure

Alkynyl Palmiti...

CAS#:99208-90-9

Literature: Menger; Chen; Brocchini; Hopkins; Hamilton Journal of the American Chemical Society, 1993 , vol. 115, # 15 p. 6600 - 6608

~%

Alkynyl Palmitic Acid Structure

Alkynyl Palmiti...

CAS#:99208-90-9

Literature: Menger; Chen; Brocchini; Hopkins; Hamilton Journal of the American Chemical Society, 1993 , vol. 115, # 15 p. 6600 - 6608

~%

Alkynyl Palmitic Acid Structure

Alkynyl Palmiti...

CAS#:99208-90-9

Literature: Menger; Chen; Brocchini; Hopkins; Hamilton Journal of the American Chemical Society, 1993 , vol. 115, # 15 p. 6600 - 6608

~%

Alkynyl Palmitic Acid Structure

Alkynyl Palmiti...

CAS#:99208-90-9

Literature: Menger; Chen; Brocchini; Hopkins; Hamilton Journal of the American Chemical Society, 1993 , vol. 115, # 15 p. 6600 - 6608

~%

Alkynyl Palmitic Acid Structure

Alkynyl Palmiti...

CAS#:99208-90-9

Literature: Hebert; Beck; Lennox; Just Journal of Organic Chemistry, 1992 , vol. 57, # 6 p. 1777 - 1783

~%

Alkynyl Palmitic Acid Structure

Alkynyl Palmiti...

CAS#:99208-90-9

Literature: Suzuki, Hikokazu; Mori, Michiko; Shibakami, Motonari Synlett, 2003 , # 14 p. 2163 - 2166

 Customs

HS Code 2916190090
Summary 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

 Synonyms

15-Hexadecyanoic acid
15-Hexadecynoic acid
15-Hexadecyn-1-oic acid
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