Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2

Modify Date: 2024-01-05 12:00:49

Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2 structure	Common Name	Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2
	CAS Number	99566-27-5	Molecular Weight	1081.27
	Density	1.38 g/cm3	Boiling Point	N/A
	Molecular Formula	C₅₄H₇₆N₁₄O₁₀	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2

Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, interacts with two distinct G-protein-coupled receptors, NPFF(1) and NPFF(2) and has wide variety of physiological functions in the brain including central cardiovascular and neuroendocrine regulation[1][2].

Name	Neuropeptide FF
Synonym	More Synonyms

Description	Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, interacts with two distinct G-protein-coupled receptors, NPFF(1) and NPFF(2) and has wide variety of physiological functions in the brain including central cardiovascular and neuroendocrine regulation[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Mankus JV, et al. Nonpeptide ligands of neuropeptide FF: current status and structural insights. Future Med Chem. 2012 Jun;4(9):1085-92. [2]. Jhamandas JH, et al. Role of neuropeptide FF in central cardiovascular and neuroendocrine regulation. Front Endocrinol (Lausanne). 2013 Feb 7;4:8.

Description

Related Catalog

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

References

[1]. Mankus JV, et al. Nonpeptide ligands of neuropeptide FF: current status and structural insights. Future Med Chem. 2012 Jun;4(9):1085-92.

[2]. Jhamandas JH, et al. Role of neuropeptide FF in central cardiovascular and neuroendocrine regulation. Front Endocrinol (Lausanne). 2013 Feb 7;4:8.

Density	1.38 g/cm3
Molecular Formula	C₅₄H₇₆N₁₄O₁₀
Molecular Weight	1081.27
Exact Mass	1080.59000
PSA	412.10000
LogP	4.54270
Index of Refraction	1.656
Storage condition	−20°C
Water Solubility	Soluble to 0.50 mg/ml in water.

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WGK Germany	3

The anti-inflammatory potential of neuropeptide FF in vitro and in vivo.

Peptides 47 , 124-32, (2013)

Neuropeptide FF (NPFF) has many functions in regulating various biological processes. However, little attention has been focused on the anti-inflammatory effect of this peptide. In the present study, ...

Intracerebroventricular administration of 26RFa produces an analgesic effect in the rat formalin test.

Peptides 30(9) , 1683-8, (2009)

GPR103 is one of the orphan G protein-coupled receptors. Recently, an endogenous ligand for GPR103, 26RFa, was identified. Many 26RFa binding sites have been observed in various nuclei of the brain in...

Pressor and tachycardic responses to intrathecal administration of neuropeptide FF in anesthetized rats.

Peptides 31(4) , 683-8, (2010)

Neuropeptide FF (NPFF) belongs to a neuropeptide family including two precursors (pro-NPFF(A) and pro-NPFF(B)) and two receptors (NPFF(1) and NPFF(2)). NPFF and NPFF receptor mRNAs have been reported ...

H-PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE-NH2

ninamide

NPFF

PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE AMIDE

F-8-F-NH2

PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE-NH2

MFCD00076704

F-8-F-NH2,NPFF,F-8-F-aMide

TC Mps1 12

Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2