The Journal of organic chemistry

Bulky trialkylsilyl acetylenes in the Cadiot-Chodkiewicz cross-coupling reaction

JP Marino, HN Nguyen

Index: Marino, Joseph P.; Nguyen, Hanh Nho Journal of Organic Chemistry, 2002 , vol. 67, # 19 p. 6841 - 6844

Full Text: HTML

Citation Number: 96

Abstract

Bulky trialkylsilyl-protected alkynes such as triethylsilyl (TES), tert-butyldimethylsilyl (TBS), and triisopropylsilyl (TIPS) acetylenes underwent the Cadiot-Chodkiewicz cross-coupling reaction with different bromoalkynes to form a variety of synthetically useful unsymmetrical diynes in good yields. The diyne alcohol 10 was transformed regio-and stereoselectively into enynes by hydrotelluration, carbometalation, and reduction reactions.

Related Articles:

ZnII??and AuI??Catalyzed Regioselective Hydrative Oxidations of 3??En??1??ynes with Selectfluor: Realization of 1, 4??Dioxo and 1, 4??Oxohydroxy Functionalizations

[Jadhav, Appaso Mahadev; Gawade, Sagar Ashok; Vasu, Dhananjayan; Dateer, Ramesh B.; Liu, Rai-Shung Chemistry - A European Journal, 2014 , vol. 20, # 7 p. 1813 - 1817]

ZnII??and AuI??Catalyzed Regioselective Hydrative Oxidations of 3??En??1??ynes with Selectfluor: Realization of 1, 4??Dioxo and 1, 4??Oxohydroxy Functionalizations

[Jadhav, Appaso Mahadev; Gawade, Sagar Ashok; Vasu, Dhananjayan; Dateer, Ramesh B.; Liu, Rai-Shung Chemistry - A European Journal, 2014 , vol. 20, # 7 p. 1813 - 1817]

More Articles...