OXIMES OF αω??DIQUATERNARY ALKANE SALTS AS ANTIDOTES TO ORGANOPHOSPHATE ANTICHOLINESTERASES

WK Berry, DR Davies, AL Green

Index: Berry et al. British Journal of Pharmacology and Chemotherapy, 1959 , vol. 14, p. 186,187

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Citation Number: 37

Abstract

METHODS Preparation of Oximes.-2-Hydroxyiminomethyl-N-methylpyridinium methanesulphonate was prepared as described by Davies, Green, and Willey (1959). Symmetrical compounds of the formula (I), but in which the position of the hydroxyiminomethyl groups in the rings was varied, were obtained by the method of Poziomek et al.(1958) from the appropriate pyridine aldoxime. For compounds with the ...