Chemical Communications

New method to prepare very stable and biocompatible fluorescent silica nanoparticles

SW Ha, CE Camalier, GR Beck Jr, JK Lee

Index: Ha, Shin-Woo; Camalier, Corinne E.; Beck Jr., George R.; Lee, Jin-Kyu Chemical Communications, 2009 , # 20 p. 2881 - 2883

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Citation Number: 52

Abstract

A new synthetic method has been developed to prepare fluorescent silica nanoparticles without employing isothiocyanated dye molecules and (3-aminopropyl) triethoxysilane (APS) for the thiourea linkage formation; the resulting fluorescent silica nanoparticles show excellent photochemical, thermal and pH stabilities and a good biocompatibility with over 85% viability from various cell types.

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