Synthesis and anticancer activity of thiosubstituted purines

A Kowalska, M Latocha, K Pluta

Index: Kowalska, Alicja; Pluta, Krystian Heterocycles, 2012 , vol. 85, # 10 p. 2473 - 2483

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Abstract

Abstract New thiopurines with the propargylthio, pyrrolidinobutynylthio, sulfenamide, and sulfonamide groups in the pyrimidine ring were synthesized. The anticancer activity of these compounds and previously obtained 2-or 6-substituted azathioprine analogs and