Synthesis of novel indole hydrazone derivatives and evaluation of their antiplatelet aggregation activity

…, K Haj Mohammad Ebrahim Tehrani, S Amidi…

Index: Mashayekhi, Vida; Tehrani, Kamaleddin Haj Mohammad Ebrahim; Amidi, Salimeh; Kobarfard, Farzad Chemical and Pharmaceutical Bulletin, 2013 , vol. 61, # 2 p. 144 - 150

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Citation Number: 19

Abstract

Based on the existing reports regarding the antiplatelet aggregation activity of hydrazone derivatives, a series of indole hydrazone derivatives were considered as potential antiplatelet agents and synthesized. The structures of the synthesized compounds were confirmed by spectral data and elemental analysis. The new indole hydrazone derivatives were evaluated for their ability to inhibit platelet aggregation induced by adenosine ...