Nickel-catalysed electrochemical coupling of 2-and 3-bromothiophene with alkyl and alkenyl halides

M Durandetti, J Périchon, JY Nédélec

Index: Durandetti, Muriel; Perichon, Jacques; Nedelec, Jean-Yves Tetrahedron Letters, 1997 , vol. 38, # 50 p. 8683 - 8686

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Citation Number: 13

Abstract

2-or 3-bromothiophene are efficiently coupled with activated alkyl chlorides (α-chloroesters, αchloroketones, α-chloronitriles), benzyl chloride or vinyl halides, in a one step electrochemical reaction, using the sacrificial anode process and catalysis by NiBr2-2, 2′∔ pyridine (bipy).