Synthesis and antiviral activity of substituted quercetins

M Thapa, Y Kim, J Desper, KO Chang…

Index: Thapa, Mahendra; Kim, Yunjeong; Desper, John; Chang, Kyeong-Ok; Hua, Duy H. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 353 - 356

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Citation Number: 33

Abstract

Influenza viruses are important pathogens that cause respiratory infections in humans and animals. In addition to vaccination, antiviral drugs against influenza virus play a significant role in controlling viral infections by reducing disease progression and virus transmission. Plant derived polyphenols are associated with antioxidant activity, anti-carcinogenic, and cardio-and neuro-protective actions. Some polyphenols, such as resveratrol and ...