Synthesis and antifungal activity of some amide and urea derivatives of bromal and dichloroacetaldehyde

WD Easterly, MW Jordin, WS Dorsey…

Index: Easterly Jr.; Jordin; Dorsey; Clark Journal of pharmaceutical sciences, 1965 , vol. 54, # 9 p. 1358 - 1361

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Citation Number: 2

Abstract

Abstract Seventeen amide and urea derivatives of bromal and dichloroacetaldehyde and one brominated derivative of butyl acrylamide were synthesized and their physical constants determined. These compounds were subjected to tests for antifungal activity toward Trichophyton rubrum, Microsporum gypsum, and Aspergillus niger. All but one of the bromal compounds studied showed fungus-inhibiting properties; of the dichloroacetaldehyde ...