Synlett

A Facile One-Pot Three-Component Synthesis of Macrocyclic Imidazolidines by [3+ 2] Cycloaddition Reaction of Azomethine Ylides

S Kathiravan, R Raghunathan

Index: Kathiravan, Subban; Raghunathan, Raghavachary Synlett, 2009 , # 7 p. 1126 - 1130

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Citation Number: 9

Abstract

Abstract One-pot three-component synthesis of novel macrocyclic imidazolidines has been accomplished in good yields via a facile [3+ 2] cycloaddition reaction of azomethine ylide, derived from paraformaldehyde and sarcosine, with various macrocyclic imines as dipolarophiles. The effect of solvent on the [3+ 2]-dipolar cycloaddition reaction is also studied.

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