A practical and versatile approach toward a one-pot synthesis of 2, 3-disubstituted 4 (3H)-quinazolinones

…, P Salehi, M Bahramnejad, M Alizadeh

Index: Dabiri, Minoo; Salehi, Peyman; Bahramnejad, Mahboobeh; Alizadeh, Mohsen Monatshefte fur Chemie, 2010 , vol. 141, # 8 p. 877 - 881

Full Text: HTML

Citation Number: 22

Abstract

Abstract An effective one-pot three-component route to 4 (3 H)-quinazolinones from commercially available starting materials is reported. Thus, isatoic anhydride reacted with ammonium acetate or primary amines and aldehydes in the presence of iodine to produce the corresponding quinazolinone derivatives in moderate to good yields. Graphical Abstract

Related Articles:

Pd (II)-Catalyzed Carbonylation of C (sp3)− H Bonds: A New Entry to 1, 4-Dicarbonyl Compounds

[Giri, Ramesh; Lam, Jonathan K.; Yu, Jin-Quan Journal of the American Chemical Society, 2010 , vol. 132, # 2 p. 686 - 693]

Palladium-catalyzed cyclocarbonylation of o-iodoanilines with imidoyl chlorides to produce quinazolin-4 (3H)-ones

[Zheng, Zhaoyan; Alper, Howard Organic Letters, 2008 , vol. 10, # 5 p. 829 - 832]

Sulfate Radical Anion (SO4•–) Mediated C (sp3)–H Nitrogenation/Oxygenation in N-Aryl Benzylic Amines Expanded the Scope for the Synthesis of Benzamidine/ …

[Wang, Yi-Feng; Zhang, Feng-Lian; Chiba, Shunsuke Organic Letters, 2013 , vol. 15, # 11 p. 2842 - 2845]

Synthesis and anti-inflammatory activity of 2, 3-diaryl-4 (3H)-quinazolinones

[Yadav; Shirude; Parmar; Balaraman; Giridhar Chemistry of Heterocyclic Compounds, 2006 , vol. 42, # 8 p. 1038 - 1045]

Synthesis of Quinazolin-4 (3 H)-ones via Amidine N-Arylation

[Li, Bryan; Samp, Lacey; Sagal, John; Hayward, Cheryl M.; Yang, Christine; Zhang, Zhijun Journal of Organic Chemistry, 2013 , vol. 78, # 3 p. 1273 - 1277]

More Articles...