Tetrahedron Letters

The cation exchange resin-promoted coupling of alkynes with aldehydes: one-pot synthesis of α, β-unsaturated ketones

JS Yadav, BVS Reddy, P Vishnumurthy

Index: Yadav; Subba Reddy; Vishnumurthy Tetrahedron Letters, 2008 , vol. 49, # 29-30 p. 4498 - 4500

Full Text: HTML

Citation Number: 17

Abstract

Alkynes undergo smooth coupling with aldehydes in the presence of Amberlyst-15® at room temperature to produce the corresponding α, β-unsaturated ketones in high yields with E- geometry. The use of an inexpensive, readily available, and recyclable cation exchange resin makes this method quite simple and convenient.

Related Articles:

Efficient, direct α-methylenation of carbonyls mediated by diisopropylammonium trifluoroacetate

[Bugarin, Alejandro; Jones, Kyle D.; Connell, Brian T. Chemical Communications, 2010 , vol. 46, # 10 p. 1715 - 1717]

Palladium??Catalyzed Synthesis of Aryl Ketones from Boronic Acids and Carboxylic Acids Activated in situ by Pivalic Anhydride

[Goossen, Lukas J.; Ghosh, Keya European Journal of Organic Chemistry, 2002 , # 19 p. 3254 - 3267]

A convenient method for preparing aromatic α, β-unsaturated ketones from α, β-unsaturated acyl chlorides and arylboronic acids via Suzuki-Miyaura type coupling …

[Urawa, Yoshio; Nishiura, Katsutoshi; Souda, Shigeru; Ogura, Katsuyuki Synthesis, 2003 , # 18 p. 2882 - 2885]

Preparation of α-methylene ketones by direct methylene transfer

[Rodrigues, J. Augusto R.; Siqueira-Filho, Ezequias P.; De Mancilha, Moacir; Moran, Paulo J. S. Synthetic Communications, 2003 , vol. 33, # 2 p. 331 - 340]

Superacid-catalyzed electrocyclization of 1-phenyl-2-propen-1-ones to 1-indanones. Kinetic and theoretical studies of electrocyclization of oxonium-carbenium …

[Suzuki, Takayoshi; Ohwada, Tomohiko; Shudo, Koichi Journal of the American Chemical Society, 1997 , vol. 119, # 29 p. 6774 - 6780]

More Articles...