Synthesis of 3-aminopyrazinone mediated by 2-pyridylthioimidate-ZnCl2 complexes. Development of an efficient route to a thrombin inhibitor

…, DJ Mathre, JR Chilenski, B Mao…

Index: Zhou, X.-X.; Welch, C.J.; Chattopadhyaya, J. Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 10 p. 806 - 816

Full Text: HTML

Citation Number: 12

Abstract

... The Journal of Organic Chemistry. ... Departments of Process Research and Department of Analytical Research, Merck Research Laboratories, PO Box 2000, Rahway, New Jersey 07065. J. Org. Chem. , 2003, 68 (23), pp 8838 ...

Related Articles:

Synthesis and solution conformation studies of the modified nucleoside N 4, 2′-O-dimethylcytidine (m 4 Cm) and its analogues

[Mahto, Santosh K.; Chow, Christine S. Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 19 p. 8795 - 8800]

Reductive monoalkylation of aromatic amines via amidine intermediates

[Zhang, Jianxing; Chang, Hui-Min; Kane, Robert R. Synlett, 2001 , # 5 p. 643 - 645]

Convenient intermediates for the preparation of C-4 modified derivatives of pyrimidine nucleosides

[Miah, Anwar; Reese, Colin B.; Song, Quanlai Nucleosides and Nucleotides, 1997 , vol. 16, # 1-2 p. 53 - 65]

Transformations of thiopyrimidine and thiopurine nucleosides following oxidation with dimethyldioxirane

[Saladino, Raffaele; Mincione, Enrico; Crestini, Claudia; Mezzetti, Maurizio Tetrahedron, 1996 , vol. 52, # 19 p. 6759 - 6780]

Convenient intermediates for the preparation of C-4 modified derivatives of pyrimidine nucleosides

[Miah, Anwar; Reese, Colin B.; Song, Quanlai Nucleosides and Nucleotides, 1997 , vol. 16, # 1-2 p. 53 - 65]

More Articles...