The synthesis of secondary nitramines by the nitrolysis of N, N-disubstituted amides

JH Robson, J Reinhart

Index: Robson; Reinhart Journal of the American Chemical Society, 1955 , vol. 77, p. 2453,2455

Full Text: HTML

Citation Number: 32

Abstract

The nitrolysis of N, K-disubstituted amides in trifluoroacetic anhydride has been further investigated. When the substituents are n-alkyl groups, the nitrolysis of acetamides, methanesulfonamides and benzenesulfonamides gives almost quantitative yields of the corresponding secondary nitramines. The nitrolysis, however, is retarded easily both by steric hindrance from the N-alkyl groups and by electronegative substituents.