Tetrahedron letters

Microwave-mediated solventless synthesis of new derivatives of marine alkaloid Leucettamine B

JR Chérouvrier, F Carreaux, JP Bazureau

Index: Cherouvrier, Jean-Rene; Carreaux, Francois; Bazureau, Jean Pierre Tetrahedron Letters, 2002 , vol. 43, # 19 p. 3581 - 3584

Full Text: HTML

Citation Number: 30

Abstract

New access to N-alkyl derivatives of the marine alkaloid Leucettamine B are described using two three-step convergent routes. For the formation of the 2-amino imidazolone ring, the key steps involve solvent-free condensations under microwaves and guanylation reactions with non-sterically hindered primary amines.

Related Articles:

Facile conversion of amino acids into 1-alkyl imidazole-2-thiones, and their oxidative desulfurization to imidazoles with benzoyl peroxide

[Wolfe, Derek M.; Schreiner, Peter R. Synthesis, 2007 , # 13 p. 2002 - 2008]

Substituted 2-thioxoimidazolidin-4-ones and imidazolidine-2, 4-diones as fatty acid amide hydrolase inhibitors templates

[Ryczek, J. Polish Journal of Chemistry, 1994 , vol. 68, # 12 p. 2599 - 2604]

Hydrogen bonded dimers vs. one-dimensional chains in 2-thiooxoimidazolidin-4-one (thiohydantoin) drug derivatives

[CrystEngComm, , vol. 12, # 6 p. 1730 - 1739]

Substituted 2-thioxoimidazolidin-4-ones and imidazolidine-2, 4-diones as fatty acid amide hydrolase inhibitors templates

[Journal of Medicinal Chemistry, , vol. 49, # 1 p. 417 - 425]

Base catalyzed cyclization of substituted esters of hydantoic and thiohydantoic acids

[Kavalek, Jaromir; Machacek, Vladimir; Svobodova, Gabriela; Sterba, Vojeslav Collection of Czechoslovak Chemical Communications, 1986 , vol. 51, # 2 p. 375 - 390]

More Articles...