Chemistry Letters

Formal anti-Markovnikov Hydroamination of Terminal Aryl Alkynes with Pinacolborane and Hydroxylamines via Zr/Cu Sequential Catalysis

R Sakae, K Hirano, T Satoh, M Miura

Index: Sakae, Ryosuke; Hirano, Koji; Satoh, Tetsuya; Miura, Masahiro Chemistry Letters, 2013 , vol. 42, # 10 p. 1128 - 1130

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Citation Number: 9

Abstract

We have developed sequential Zr/Cu catalysis involving regioselective hydroboration and electrophilic amination for the formal anti-Markovnikov hydroamination of terminal aryl alkynes. The reaction system can provide a facile access to enamines from terminal acetylenes with high regioselectivity under mild conditions.

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