An enantiocontrolled synthesis of pyrrolizidines,(−)-platynecine and (−)-hadinecine

SH Kang, GT Kim, YS Yoo

Index: Kang, Sung Ho; Kim, Geun Tae; Yoo, Yong Sang Tetrahedron Letters, 1997 , vol. 38, # 4 p. 603 - 606

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Citation Number: 16

Abstract

Trisubstituted allylic alcohols 13 and 14 have been converted into a single isomeric trans- oxazoline 16via an intramolecular iodoamidation of the corresponding trichloro- acetimidates, which have been elaborated into (−)-platynecine 1 and (−)-hadinecine 2via a common intermediate pyrrolizidine 3.