Chemische Berichte

o??(α??Benzotriazolylalkyl) phenols: Versatile Intermediates for the Synthesis of Substituted Phenols

AR Katritzky, X Lan, JN Lam

Index: Katritzky, Alan R.; Lan, Xiangfu; Lam, Jamshed N. Chemische Berichte, 1991 , vol. 124, # 8 p. 1809 - 1817

Full Text: HTML

Citation Number: 47

Abstract

Abstract Phenols and naphthols are benzotriazolylmethylated by 1-(hydroxymethyl)-1H- benzotriazole (13)(a formaldehyde derivative) in the o-or (if both o-positions are occupied) in the p-position. The reaction can be extended to other aldehydes in the case of the naphthols. The methylene group in the o-(benzotriazolylmethyl) phenols can be lithiated (but only after trimethylsilyl protection of the hydroxy group) and then substituted by various ...

Related Articles:

Highly selective benzylations of β-naphthoxide anion in heterogeneous media

[Bram, G.; Loupy, A.; Sansoulet, J.; Vaziri-Zand, F Tetrahedron Letters, 1984 , vol. 25, # 44 p. 5035 - 5038]

Microwave-assisted solid-liquid phase alkylation of naphthols

[Balint, Erika; Kovacs, Orsolya; Drahos, Laszlo; Keglevich, Gyoergy Letters in Organic Chemistry, 2013 , vol. 10, # 5 p. 330 - 336]

An efficient method for the preparation of versatile building blocks: 1-substituted 2, 2-dimethoxyethylamine hydrochlorides

[Liu, Bo; Su, Deyong; Cheng, Guolin; Liu, Hui; Wang, Xinyan; Hu, Yuefei Synthesis, 2009 , # 19 p. 3227 - 3232]

Synthetic routes to derivatives of polycyclic aromatic hydrocarbons using isobenzofurans as transient reactive intermediates

[Smith, James G.; Welankiwar, Sudha S.; Shantz, Barry S.; Lai, Eric H.; Chu, Noreen G. Journal of Organic Chemistry, 1980 , vol. 45, # 10 p. 1817 - 1824]

Convenient Synthesis of 1??Arylmethyl??2??naphthols

[Paul, Nawal K.; Dietrich, Lindsay; Jha, Amitabh Synthetic Communications, 2007 , vol. 37, # 6 p. 877 - 888]

More Articles...