Vanadium-catalyzed cross-coupling reactions of alkyl halides with aryl Grignard reagents

S Yasuda, H Yorimitsu, K Oshima

Index: Yasuda, Shigeo; Yorimitsu, Hideki; Oshima, Koichiro Bulletin of the Chemical Society of Japan, 2008 , vol. 81, # 2 p. 287 - 290

Full Text: HTML

Citation Number: 19

Abstract

Vanadium (III) chloride catalyzed cross-coupling reactions of alkyl halides with arylmagnesium bromides. Various arylmagnesium bromides, except for an ortho-substituted arylmagnesium reagent, could be used for the reaction. Among alkyl halides tested, cyclohexyl halides and primary alkyl halides were good substrates. The reactions likely proceed via carbon-centered radical intermediates.

Related Articles:

Intramolecular carbolithiation promoted by a DTBB-catalysed chlorine–lithium exchange

[Yus, Miguel; Ortiz, Rosa; Huerta, Fernando F. Tetrahedron, 2003 , vol. 59, # 43 p. 8525 - 8542]

Synthesis and evaluation of 4-alkylanilines as mammary tumor inhibiting aromatase inhibitors

[Hartmann; Batzl European Journal of Medicinal Chemistry, 1992 , vol. 27, # 5 p. 537 - 544]

Electroreductive cyclization reactions of 6-chloro-1-phenyl-1-hexyne and 6-chloro-1-phenyl-1, 2-hexadiene at a mercury cathode in dimethylformamide

[Moore,W.M. et al. Journal of the American Chemical Society, 1975 , vol. 97, # 17 p. 4954 - 4960]

Radical reactions in organoboron chemistry II—Inter-and intramolecular addition of carbon centered radicals to alkenylboranes

[Guennouni; Lhermitte; Cochard; Carboni Tetrahedron, 1995 , vol. 51, # 25 p. 6999 - 7018]

Intramolecular carbolithiation promoted by a DTBB-catalysed chlorine–lithium exchange

[Yus, Miguel; Ortiz, Rosa; Huerta, Fernando F. Tetrahedron, 2003 , vol. 59, # 43 p. 8525 - 8542]

More Articles...