Alkylation of. ALPHA.-Halo Diketones via Enol Phosphate Intermediate

JY Onishi, T Takuwa, T Mukaiyama

Index: Onishi, Jim Yoshitaka; Takuwa, Tomofumi; Mukaiyama, Teruaki Chemistry Letters, 2003 , vol. 32, # 11 p. 994 - 995

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Citation Number: 5

Abstract

A new approach to synthesis of substituted alkenes is always of interest in synthetic organic chemistry, specifically in the area of natural product synthesis such as terpenes1 and prostaglan- dins2 when reaction conditions are deemed inefficient or inap- propriate by conventional methods. The preparation of , -unsaturated carbonyl compounds using organocuprates by 1,4-addition to unsaturated compounds bearing leaving groups such as halogen,3 ...